Health

How healthy is your liver, really?

Posted On:

January 8, 2024

Posted By:

Mary Cristine

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Fatty liver, a condition characterized by the accumulation of excess fat in liver cells, is a growing concern in modern society due to lifestyle factors and dietary choices. Concurrently, athletes and fitness enthusiasts are always in pursuit of supplements that can enhance performance and promote overall health. Enter Trimethylglycine, commonly known as TMG, a compound with potential benefits for both athletic performance and liver health.

Understanding Fatty Liver:

Fatty liver can be categorized into two types: alcoholic fatty liver disease (AFLD) and non-alcoholic fatty liver disease (NAFLD). NAFLD, often associated with obesity, poor diet, and sedentary lifestyles, is on the rise. If left untreated, it can progress to more severe conditions, including liver inflammation and scarring.

The Role of TMG in Liver Health:

  • Homocysteine Regulation:
    • TMG is a methyl donor, meaning it assists in the transfer of methyl groups in various biochemical reactions.
    • It helps regulate homocysteine levels, a compound associated with liver damage when elevated.
    • By supporting methylation pathways, TMG aids in detoxification processes crucial for liver health.
  • Antioxidant Properties:
    • TMG exhibits antioxidant properties that can counteract oxidative stress, a contributing factor to liver damage.
    • Antioxidants play a vital role in protecting liver cells from inflammation and damage caused by free radicals.

TMG and Athletic Performance:

  • Energy Production:
    • TMG contributes to the methylation cycle, a key process in energy production.
    • Athletes may benefit from enhanced energy metabolism, potentially reducing fatigue and improving overall performance.
  • Muscle Function:
    • Improved methylation processes support protein synthesis, essential for muscle repair and growth.
    • Athletes engaging in intense training may experience better recovery and reduced muscle soreness with TMG supplementation.
  • Homocysteine and Exercise:
    • Elevated homocysteine levels are associated with cardiovascular risks, which can impact athletic performance.
    • TMG’s role in homocysteine regulation may contribute to better cardiovascular health, supporting endurance and overall fitness.

  • Diet: TMG is found in foods like beets, whole grains, and leafy greens. However, supplementation may be necessary to achieve therapeutic levels.


Trimethylglycine emerges as a promising supplement for athletes seeking improved performance and individuals looking to support liver health, particularly in the context of fatty liver. By addressing both athletic performance and liver health, TMG represents a multifaceted approach to well-being, potentially offering benefits to those navigating the balance between fitness and overall health.

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